Advent of Ascension Wiki
Advent of Ascension Wiki
Poison Rune
Poison Rune.png
Rarity color Common
Renewable Yes
Stackable Yes (64)
Version added 1.1
ID aoa3:poison_rune

The Poison Rune is an item used primarily as ammunition for staves.


Rune Shrine[]

Using Unpowered Runes or Charged Runes on a Rune Shrine that is centered on a Poison Rune Shrine, will convert those Runes into Poison Runes. The player can only convert Runes into Poison Runes if their Runation level is 22 or higher.

Mob Drops[]

Poison Runes can be obtained as a drop from the following mobs:

Rune Box[]

Poison Runes can be found when opening a Rune Box.

Rune Randomizer[]

Using Unpowered Runes or Charged Runes on a Rune Randomizer has a chance to convert them into Poison Runes.



Poison Runes are required as ammunition for the following Staves:

Additionally, Runic Sword can consume Poison Runes when attacking to poison mobs on hit.


Item Ingredients Recipe
Poison Staff 1 Poison Rune +
2 Sticks
Poison Rune
Poison Staff


Item Ingredients Recipe
Spraggy Slab 1 Draggy Slab +
1 Poison Rune +
1 Blank Slab
Draggy Slab
Poison Rune
Spraggy Slab
Blank Slab
This recipe is shapeless; the ingredients may be placed in any arrangement in the crafting grid.


Crafting a Poison Rune with a vanilla Banner and a dye will give the Banner a pattern that resembles the Poison Rune's symbol.

Rune Templar[]

Using a Poison Rune and Runic Energy on a green Rune Templar will activate it. This will not consume the Poison Rune, only the Runic Energy.